Updates in Version 1.2019 of the NCCN Guidelines for Breast Cancer from Version 4.2018 include: Continued UPDATES General: Recommendations for Lobular Carcinoma in Situ (LCIS-1) were removed from the NCCN Guidelines for Breast Cancer; see the NCCN Guidelines for Breast Cancer Screening and Diagnosis. Soft Tissue Sarcoma. DCIS-1 Phyllodes tumors (FILL-odes or full-OH-deez) can also be spelled phylloides tumors (full-OY-deez). Available at: www.nccn.org (Accessed on February 22, 2016). Without prospective trials to guide management, NCCN also recommends consideration of radiation therapy (XRT). Version 2.2016. According to NCCN guidelines wide excision means excision with the intention of obtaining surgical margins ≥1 cm. Malignant phyllodes tumors: a review of 752 cases. NCCN Clinical practice guidelines in oncology (NCCN Guidelines). Those with an associated invasive cancer should undergo adjuvant systemic therapy based on the stage and hormone receptor status, as outlined online, in these guidelines, at www.NCCN.org . Patient management was examined using NCCN guidelines to determine the relative adherence of providers to established treatment recommendations . Phyllodes tumors are most common in women in their 40s, but women of any age can have them. Current guidelines for phyllodes tumor recommend against axillary dissection and chemotherapy use. These are rare breast tumors that start in the connective (stromal) tissue of the breast. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Breast Cancer include up-to-date recommendations for the clinical management of patients with carcinoma in situ, invasive breast cancer, Paget disease, phyllodes tumor, inflammatory breast cancer, and breast cancer … This follows the same breast cancer follow up protocol defined by NCCN guidelines. The median follow up was 11 months with a range of 4-33 months. malignant phyllodes tumor of the breast were followed up at 3 monthly intervals. Updates in Version 2.2016 of the NCCN Guidelines for Breast Cancer from Version 1.2016 include: Additionally, they recommend cautious use of radiotherapy, particularly in young patients. Locally recurrent breast mass following excision of phyllodes tumor Metastatic disease 1 Pathology should be reviewed to assess for fibroadenoma versus phyllodes (phyllodes benign, borderline and malignant). The National Comprehensive Cancer Network (NCCN ) makes no representations or Grabowski J, Salzstein SL, Sadler GR, Blair SL. Am Surg 2007; 73:967. INTRODUCTION: National Comprehensive Cancer Network (NCCN) guidelines recommend wide excision without axillary staging to treat phyllodes tumors of the breast. National Comprehensive Cancer Network (NCCN). 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